With the star power of folks like Dakota Fanning, Zac Efron, Kristen Bell and Vanessa Hudgens fighting against cancer, that disease doesn't have a chance. Efron, Bell, Hudgens and Fanning lent their voices to Stand Up to Cancer's new "Change the Odds" public service announcement, which focuses on the unfortunately high odds of being diagnosed with cancer.

The video, co-directed by (500) Days of Summer's Marc Webb and music video helmsman Rich Lee, also highlights Stand Up to Cancer's upcoming fundraiser for cancer research, set to air on multiple networks September 10 at 8 PM/7 PM central.